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The formal inclusion in scientific papers of a section devoted to 3Rs may increase knowledge and eventually adherence to this principle by scientists.

In fact, while education may increase knowledge of evolution, it may have a polarizing effect on evolutionary acceptance, driving such individuals even further into a non-accepting stance on evolution (Baker [2013]).

The communication-focused intervention was not effective in promoting the uptake of screening, and the authors suggest that while such strategies may increase knowledge and awareness of screening, additional interventions or resources may be needed to change behaviour.

Interest in HIV self-testing is high and may increase knowledge of HIV status; however, empirical research on selftesting is limited, resulting in lack of evidence on which to base policy recommendations.

Undergraduate IPE interventions appear to be generally well received by students, and may increase knowledge and skills required for collaborative practice, improve student attitudes towards collaboration, and also improve clinical behaviour and patient care [ 1, 20– 20].

A meta-analysis of the effectiveness of Continuing Medical Education (CME) found that lectures had no impact on clinician performance or patient outcomes, even though they may increase knowledge short-term [ 31].

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In learning more about autism, a disorder that in some form affects at least 425,000 Americans under 18, scientists may also increase knowledge about language development, emotion, even friendship and love.

Even though analysis of molecular markers may greatly increase knowledge about genetic contingency and reproductive isolation, evidence for adaptive divergence in most cases remains scarce and circumstantial, unless demanding tests such as common garden experiments are conducted.

Although these PPARγ mutations are rare in humans, these patients exist and in fact it may be possible that their prevalence may increase as increased knowledge allows targeting of specific subsets of patients such as, for example, patients with cardiac phenotypes.

The overall consideration derived from the present data, is that the evaluation of FM comorbidity may increase the knowledge about the basic mechanisms of chronicization and the expression of central sensitization phenomena in the different primary headache subtypes.

Nonetheless, metabolomics is a powerful tool which may increase the knowledge of how metabolites are altered in living organisms in response to exposures, mechanisms of toxicity, biomarkers of toxic effects, and can be used in developing models for toxicity prediction.

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