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Comorbidities of depression and anxiety may increase headache frequency in migraineurs [8].
This transformation may increase headache related disability, as well as the difficulty of treating it [13].
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Thus, in susceptible individuals, repeated migraine attacks may result in increasing headache frequency and eventually refractory chronic migraines [10].
On the other hand frequent headaches may increase distractibility, particularly in children with primary short attention span and thus further insult learning.
In some cases, the type of traumatic event a person with PTSD has experienced may increase the likelihood of headaches.
There have been reports that DIM may increase the severity of headaches in women who get migraine.
There are anecdotal reports that DIM may increase the severity of migraine headaches.
A different hypothesis is that frequent headaches by themselves may increase distractibility and irritation especially in children with a primary short attention span, and thus impose a further insult on the challenge of learning.
Weight gain is not associated with migraine prevalence but may be associated with increased headache frequency.
Realising that medication overuse may be contributing to increased headache seems important for the successful treatment of MOH and thus more research on this stage is needed.
Increased health awareness and diagnosis rates may increase the prevalence of various conditions including headache.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com