Sentence examples for may increase actin from inspiring English sources

Although it has been argued that cofilin may increase actin barbed ends not only through its severing activity [13], [45] but also by increasing the G-actin supply [23], the data (Fig. 7) demonstrate the crucial role of cofilin in stimulus-evoked lamellipod actin assembly, which is conserved between breast carcinoma cell lines and XTC fibroblasts.

One possibility is that the absence of actin stress fibers in myosin IIA deficient cells (Fig. 2B) may increase the cytoplasmic actin monomer concentration that in turn promotes actin polymerization at the leading edge.

One possible explanation for this finding is that LIMK1 knockdown may increase the formation of cofilin-actin rods (Bamburg et al., 2010), stable structures that are formed only by dephospho-cofilin (Bernstein et al., 2006).

Secondly, we speculate that PIK3CA mutations may increase early tumor diagnosis by modification of the actin cytoskeleton in tumor cells.

Caveolae associate with actin filaments at the plasma membrane (Rohlich and Allison, 1976; Singer, 1979) and disruption of F-actin impaired mitogen-dependent stimulation of ERK to the same extent as cavin-3 depletion, suggesting that cavin-3 may increase caveolae abundance by anchoring caveolae to F-actin at the cell surface.

Thus, we speculate that, although the combination of PMA and apicularen A induces G2/M phase arrest by disrupting microtubule networks, increased actin reorganization may contribute to increased cell migration (Additional file 1: Movie S1).

When the number of actin filaments drops, but they are 'packed' more densely within the cell, the stiffness may increase (see Figure 8 (A)).

IL-6 may increase the permeability of endothelial cells [ 5] by changing the cell shape and rearrangement of intracellular actin fibers [ 19].

Talin-1 may trigger a conformational change in the extracellular domains of β-integrin, which may increase the affinity of β-integrin for ECM proteins by linking the cytoplasmic domains of integrin β subunits to actin filaments [ 34, 35].

If anything, it may increase.

"De-stocking activities may increase.