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Inaccuracy: rules may incorrectly classify some exemplars.
Note that numerical conditioning and round-off errors for models with large uncertainties can pose challenges and may incorrectly classify a model inconsistent.
Also, as shown in a recent paper by Lee et. al. [ 16], the degree of FDG uptake is dependant on the tumour type meaning that an arbitrary cut off value may incorrectly classify lower grade tumours.
Thus, workers who have never been diagnosed with pesticide poisoning may still have sustained high exposures or experienced pesticide-related illness; therefore using diagnosed poisoning as a criterion for inclusion in an exposed group or exclusion from a comparison group may incorrectly classify individuals.
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This suggests that, while rBBH is useful for detecting mito-nuclear orthologs (comparable with computational annotation of GO terms), our approach may miss or incorrectly classify some of the mito-nuclear genes across distantly related species.
But that still leaves untold numbers of fossils on display in museums that may be incorrectly classified.
For example, rule-out diagnoses, which are used to indicate that an individual does not have a condition, may be incorrectly classified as comorbidities.
A tumor with lymph node involvement may be incorrectly classified as stage I or II if the number of lymph nodes examined is too small.
Of note, some transplants may be incorrectly classified as an early technical failure (thus resulting in an overestimate) because of severe early rejection and associated thrombosis.
There is a risk that some patients may be incorrectly classified as having evident or suspected cognitive impairment as a result of a transient confusion related to the injury.
Nevertheless, epidemiologists and neuropathologists have reached a consensus that a pathology report of GBM is likely to be valid (although a small proportion of GBMs may be incorrectly classified as grade III [anaplastic] astrocytomas), whereas valid classification of non-GBM subtypes requires centralized pathologic review [ 10].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com