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Also, text-mining algorithms may incorrectly assign the direction (negative, unknown, or positive) of autophagy modulation, depending on whether the assay defined autophagy appropriately.
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Classifiers constructed on different randomly chosen negatives may give different results, since some unknown targets may be incorrectly assigned to the negative set.
Therefore, we may have incorrectly assigned some patients as being from the same region of the world as their physicians.
This decision represents a crucial step in the iterative probabilistic assignment of reads to haplotypes within ShoRAH – if the constituent reads of a low frequency true haplotype are just as likely to originate from a higher frequency haplotype through sequencing errors, then they may be incorrectly assigned to the higher frequency haplotype.
Therefore, some immigrant patients may have been incorrectly assigned as being Canadian-born.
It is possible that occupations may have been incorrectly assigned to an occupational code and hence assigned to an inappropriate exposure group.
The classification result may contain some errors, resulting in incorrectly assigned labels.
Finally, it may be possible to reduce the probability of incorrectly assigning reads to a sample due to sequencing errors within the tags.
Nevertheless, even when a small number of individuals are incorrectly assigned to one set or another, it may still be possible to map the disease locus [ 34], although with some loss of power.
Only 2 out of 297 dogs were incorrectly assigned and none of these mis-assignments corresponded to poodles.
Thus, we cannot rule out that some of the precursors now assigned to different contigs i.e. appears as duplicated at different unique genome locations, may in fact not be true duplicates, but just single locus sequence that has been incorrectly assigned into different contigs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com