Therefore, the current false-positive rate may be overestimated because it may include an unknown fusion partner for the RET gene.
Most likely, as is the case in so many cases in evolutionary biology, the origin of ORFans will turn out to be non-exclusive [ 31], and may include other yet-unknown mechanisms.
Reasons for this hypophagia may include a hitherto-unknown action of the compound to promote satiation, or alternatively be attributed to the elevated water intake of the animals, since there are at least some data suggesting that increased water consumption with meals has been found to reduce energy intake and therefore increase weight loss in obese patients.
The sequences may represent entire genomes and may include both known and unknown sequences or may be collections of sequences of cytokines.
The total number of adherents to Santería Cuba's main religious movement is unknown but may include between one-half and seven-tenths of the population.
Predisposing factors are currently unknown but may include prior use of corticosteroid, necrotizing retinitis and/or high spirochaetal load.
Reasons for this are unknown but may include CTX supply shortfalls and clinician concerns about CTX drug resistance development [32], [33], [63].
However, the vital status of those patients LTF is often unknown, and may include negative outcomes (such as mortality) and non-negative outcomes (such as transfers).
The anatomical sites of action for the peripherally accessible, orexigenic TrkB signal are currently unknown, but may include the enteric nervous system, the pancreatic and gut neuro-endocrine system, the vagal nerve and/or the circumventricular organs.
Priming was achieved in 8 out of the 11 donors examined (Figure 2C), and reasons for the failure to induce priming in all donors are unknown, but may include the death of newly activated T cells, the HLA differences among donors, or even T cell impairing effects exerted by the virus on the immune cells from some individuals.
