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Conversely, contributing factors to cataract formation in other regions of the lens may include uncontrolled association of crystallins and the formation of high-molecular weight aggregates at the membrane (Mathias et al, 2007).
Although observational studies lack the robustness of RCTs and may include uncontrolled confounding variables [ 26], they can nevertheless yield important data to complement the results from RCTs (e.g. in the study of rare outcomes, risk factors and side effects) and provide valuable information on long-term outcomes in routine clinical practice [ 27].
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Of course, as the experiments were carried out in controlled laboratory conditions, the data may include less uncontrolled variation that would be expected in wild.
Some disorders that may raise the risk of a miscarriage include uncontrolled diabetes, high blood pressure, thyroid disease, infections, hormonal problems and problems with the uterus or cervix.
Sources of human-caused fire may include arson, accidental ignition, or the uncontrolled use of fire in land-clearing and agriculture such as the slash-and-burn farming in Southeast Asia.
Reasons may include: Fatigue.
The urban context with its particular living conditions (including uncontrolled expansion of urban slums and informal settlements, residential overcrowding, or environmental degradation) may explain these patterns.
Arrhythmias at the time of death included uncontrolled ventricular tachycardia, long QT, and torsades de pointes.
Other exclusion criteria included uncontrolled systemic disease or infection.
Others included uncontrolled nausea and vomiting.
Third, there may be uncontrolled confounding by variables not included in the model.
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