In addition, data suggest that patients who have experienced a hypoglycemic episode are likely to initiate preventive behaviors that may include modification of their dosing regimen [ 14, 16].
The latter may include modification of the intervention over time or a description of the contextual factors influencing the intervention effectiveness.
This may include modification of terminal residues and substitution of cysteine residues with alanine or other non-reactive residues such as serine to avoid potential peptide aggregation (e.g. [ 35]).
134, 135 Interestingly, breast cancer-specific alternative splicing is not restricted to splicing defects resulting in loss of protein functions, and may also include modifications that generate proteins with new functions.
Mathematically, "artificial samples" represent a subset of "fake samples", because the set "fake samples" may also include modifications of live samples [ 9, 11], for example, "artificial samples" are fingerprints produced from a mold, but the set "fake samples" contains also injured or otherwise modified live fingers and biometric samples.
Such conditions may include chromatin modifications and/or the recruitment of coregulators, since most of the AR occupied regions were also co-occupied by other TFs, which in several cases acted as coregulators of gene expression.
Nonpharmacological supportive treatments may include dietary modifications consisting of fiber supplements, such as oat bran, concentrated vegetable powder, or psyllium.
Such mechanisms of adaptation may include posttranslational modifications to proteins/enzymes, as is also known for reversible protein phosphorylation in rodent hibernation [40].
28 Initial management of mild to moderate diarrhea may include dietary modifications and the use of antidiarrheal medications, such as loperamide, octreotide, and tincture of opium.
