Sentence examples for may improve toxicity from inspiring English sources

Toxicogenomic evaluations may improve toxicity prediction of in vitro-based developmental models, such as whole embryo culture (WEC) and embryonic stem cells (ESC), by providing a robust mechanistic marker which can be linked with responses associated with developmental toxicity in vivo.

Single agent paclitaxel was also demonstrated to produce a 2-month longer MST (6.8 vs 4.8 months) in comparison with supportive care in a randomised trial with no upper limit of age for accrual (Ranson, 2000), and this drug appeared highly attractive for treating elderly patients, in view of the increasing evidence that a weekly schedule may improve its toxicity profile (Alberola et al, 2002).

Newer immunosuppressive agents may have improved toxicity profiles.

Dose intense chemotherapy may improve efficacy with acceptable toxicity.

Therefore, determination of significant associations between genomic polymorphisms and defined clinical end points (eg survival, response, toxicity) may improve the prediction of treatment success and thereby the tailoring of chemotherapy.

The standard sequence of drugs for adjuvant therapy has to date involved anthracyclines followed by taxanes, but phase II trials have recently suggested that the reverse sequence may improve efficacy and lower toxicity [ 19].

Because of the limitations of the current therapies, addition of molecular-targeted drugs, particularly to chemotherapies with acceptable toxicities, may improve the outcomes.

Targeted therapies may improve chemotherapy effectiveness without worsening toxicity.

Encapsulating artemisinin into poly lactic-co glycolic nanoparticles may improve its effectiveness and reduce toxicity.

Evidence further suggests that locoregional viral administration may improve viral efficacy while minimizing toxicity.

Using the IMRT or the SFUD plans instead of the 3-D conformal plan may improve both bowel and rectal toxicity.