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However, the mechanisms by which these antihyperglycaemic drugs may improve renal outcome beyond glycaemic control are unclear, but may involve improvements in body weight, blood pressure, renal haemodynamics and albuminuria or lipid profiles.
In conclusion, the addition of NAC to fluid resuscitation may improve renal oxygenation and attenuate microvascular dysfunction and AKI.
The addition of NAC to fluid resuscitation may improve renal oxygenation and attenuate microvascular dysfunction and AKI.
As a specific dopamine type-1 receptor agonist, fenoldopam increases renal blood flow, stimulates natriuresis and urinary output, and may improve renal function, so that it may be suitable for the treatment of severe hypertension in patients with renal failure [36].
ADH regulates urine volume and concentration and may improve renal perfusion pressure.
The present data suggest that levosimendan may improve renal function in patients with septic shock.
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This may also improve renal venous drainage as in this case, where ovarian vein embolization may result in an elevated renal venous pressure.
A reduction of IAP may also improve renal perfusion by lowering venous and retroperitoneal pressure.
Achievement and long-term maintenance of sUA <6.0 mg/dL leads to reduction of tophi and near-elimination of acute flares [ 20, 21, 25- 27], and may stabilize or improve renal function in gout patients [ 28].
Analyses of multiple clinical trials [ 2– 9] and meta-analyses [ 1, 10– 12] have suggested that, in addition to preventing and/or reducing cardiovascular events and mortality, intensive treatment of dyslipidemia with statins (HMG-CoA reductase inhibitors) may stabilize or improve renal function in patients with vascular disease, with or without pre-existing renal impairment.
This observation would suggest that a simple change in posture could provide a clinically significant improvement in the UIAP, which in turn, may improve hepatic, renal and splanchnic blood flow.
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