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Aggressive therapy for rhythm and haemodynamic abnormalities may improve long term functional status.
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Evidence also suggests that the prompt improvement in symptoms may improve long-term outcomes [ 2].
Interventions to minimizing the burden of sepsis in critically ill patients may improve long-term outcomes.
The CESAR study demonstrated that in highly specialized centers, ECMO therapy may improve long-term outcome.
However the role of stent placement after dilation is controversial because, while it may improve long-term success, the tube itself may stimulate inflammatory reaction, fibrosis and stone formation [32, 34].
While treatment may improve long-term outcomes, it does not get rid of negative outcomes entirely.
Hence, inhibition of ubiquitin-dependent degradation of topoisomerases may improve long-term therapeutic efficacy of topoisomerase-targeted drugs.
Erythropoietin (EPO) has non-hematopoietic targets, and we hypothesized that EPO may improve long-term fat graft survival because it has both pro-angiogenic and anti-apoptotic properties.
These results suggest that the inhibition of Hh signaling may improve long-term outcomes in B-ALL by targeting the clonogenic cells responsible for disease relapse.
Thus, the development of therapeutic agents that effectively target CSC may improve long-term outcomes, such as progression-free and overall survival.
Therapeutic approaches that target self-renewal may improve long-term outcomes, but few approaches have been developed that target this property.
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CEO of Professional Science Editing for Scientists @ prosciediting.com