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Collecting more spot urine samples may improve exposure assessment, but the number of samples needed to ensure reasonable exposure classification and the impact of collecting these additional specimens on participants' compliance is unknown.
As suggested by Villanueva et al. (2006a), additional information, including individual physiologic and genetic characteristics, recent relevant exposures, and direct environmental measurements, may improve exposure assessment and thus the precision of disease risk estimates associated with human exposure to disinfection byproducts.
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Collection of information on children's time activity patterns (time spent outdoors) and housing characteristics (e.g., use of air conditioning and level of ventilation) and advanced exposure modeling (LUR and kriging) may further improve exposure assessment.
Understanding such relationships may improve future exposure and risk assessments for As.
Application of a PBPK model that incorporates an inducible elimination of TCDD may improve the exposure assessments in epidemiologic studies of TCDD.
The low number might reflect surgeons' attitude of the perceived risk versus benefits from such procedures and also the low proportions of severe vaginal scarring reported (in cases of severe scarring and stenosis relaxing incisions may be necessary to improve exposure of the operative field).
For such exposures, intra- compared with interindividual variability is known to be high, and only many repeat measurements over time may give improved exposure estimates.
Adjustment for BDE-209 degradation in the GC injector resulted in stronger positive trends for BDE-206, BDE-207, and BDE-208 compared with analyses of unadjusted concentrations of these congeners, suggesting that adjustment may have improved exposure classification.
Population-specific exposure modeling may improve culturally and behaviorally specific exposure assessment, clarifying gendered exposure differences.
Because many diarrhoeic pathogens like Cryptosporidium and Giardia are zoonotic, (organisms that can be transmitted between animals and people), monitoring herds for diarrhoeal disease may improve understanding of exposure risks.
Measurement of biomarkers in cord blood improves exposure assessment and may improve our understanding of biological mechanisms during this critical window of exposure and vulnerability (Wild and Kleinjans 2003).
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