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Following the model of Kapreli and Athanasopoulos [32], mechanoreceptor damage may lead to a disturbance of sensory transmission, contributing to alterations of afferent feedback and stabilizing reflexes that may implicate increased body sway [1, 8, 25, 59].
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The properties of keratins applied in wound dressings may implicate that increased keratin levels in the MRL/MpJ mouse promote regeneration.
Our observations may implicate an increase in bone turnover with increasing ALP gene expression and, thus, a decrease in bone volume due to decreasing Tb.N.
Additionally, mRNA level of lipoprotein lipase (LPL) was markedly elevated (+ 79%) while its inhibitor, Apo-CIII was reduced (− 50%) in MCD-fed ob/ob livers, which may implicate an additional role for increased LPL-mediated FA uptake by the liver (Fig. 4E).
The mechanism underlying this observed relationship between SMR and in vivo H2O2 content requires further investigation, but may implicate mitochondrial uncoupling which can simultaneously increase SMR but reduce ROS production.
This may implicate the dual role of AP-1 in increased cell proliferation and cell death [ 48].
Since retinal ganglion cells participate in the photophobia of migraine [ 5], this intraocular increase of sodium may implicate a local retinal stimulation from elevated sodium concentrations.
Since Apo A-IV produced in CNS may exert its anorectic action, the finding of increased CSF Apo A-IV in present study may implicate an altered energy metabolism, which may be related with the weight loss in HD patients.
Our finding of an increased risk of CBC after HR-mixed FBC may implicate those aspects [ 25].
Some studies have suggested that IFN- γ concentrations are increased in the aged brain [ 44], which may implicate IFN- γ as a candidate molecule for microglial priming.
The increasing activin A/FS, an indicator of available activin activity, may implicate dysregulation of activin A and a consequent lung injury.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com