Second, viral restriction specificity may further impede identification of antiviral function especially for those restriction factors that act directly at the host virus interface (like TRIM5alpha) compared with those that may indirectly affect the immune response (like PML); for the former case, detection of antiviral activity would depend on the right combination of TRIM genes and viruses.
Also, variations in growth conditions (incubation temperature, repeated subculturing and storage) may impede accurate identification of these two species by phenotypic tests.
The potential disadvantage of radiation scattering from the primary injection site, which may impede the identification of the sentinel node, may thus be eliminated to the greatest possible extent.
Conceivably, tumour heterogeneity may impede the identification of predictive biomarkers, and the quest for personalised, or even curative treatment, and is an area of cancer research worthy of intensive and collaborative effort.
presence of faecal residues from insufficient bowel cleansing (Fig.16D E), which may obscure intraluminal processes but generally does not impede identification of strictures and assessment of mural thickness.
Embarrassment and fear of judgment can impede identification of prenatal alcohol use via face-to-face screening [ 29].
Also, variations in growth conditions including incubation temperature, repeated sub-culture, and storage may impede their accurate identification (Pasligh et al. 2008).
One important consequence of constraint at synonymous sites is that it may impede on the identification of positively selected genes and sites.
ChIP-seq of histone modifications that mark active promoters and enhancers are informative, but their typical broader peaks may impede precise screening and identification of candidate functional variants.
Exclusive testing for Stx delays specific identification of O157 STEC and may impede prompt detection of common-source outbreaks (2 – 4 ).
