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At certain concentrations, the oil layer in the media can interfere with oxygen transfer and may impede cell survival and growth (Kanmani et al. 2015).
For instance, the constitution of the bacterial cell wall may impede cell lysis and the liberation of DNA from the cell.
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The switch from an M2 to an M1 promoting environment during atherosclerosis progression may impede apoptotic cell clearance as M2 cells have greater capacity for efferocytosis [90] (Figure 1); this is through various pathways such as the expression of MR [91] and up-regulation of MER proto-oncogene tryosine kinase (MERTK) (on M2c), which is not induced on M1 macrophages [49],[92].
In addition, the downregulation of genes involved in mitotic cell cycle and cell division predicted that T. cruzi infection may impede host cell cycle progression.
Nearly two dozen states have passed laws, until now little-known, that govern research on embryos and fetuses and may impede stem cell studies.
The large cycle deformation may impede endothelial cell survival and tubulogenesis through the NAD(P H subunit p22phox pathway [25].
The sharp decrease in flux toward biosynthetic metabolic pathways and increased catabolism following Glut1 deletion suggested that Glut1 deficiency may impede B-ALL cell growth and proliferation.
In vitro and animal studies suggest that vitamin D and its metabolites may impede carcinogenesis by stimulating cell differentiation, inhibiting cell proliferation typically characterized by G0/G1 cell cycle arrest, apoptosis, and suppression of invassion, angiogenesis, and metastasis [3] [6].
While considering these extracts as candidates to be used for prevention of sexual transmission of HIV, their effect on primary vaginal keratinocytes viability is highly relevant, as vaginal epithelial cells form a part of the physical barrier that may impede the passage of cell-free or cell associated HIV-1 into sub epithelial tissues.
Further studies are required to confirm that high proportions of putative Tregs at birth and early in infancy precede sensitization and that high proportions of these cells early in life may impede the post-natal T cell maturation process.
Poorly deformable transfused red blood cells may impede microvascular flow [40].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com