As Ahr/Arnt promoter binding sites are enriched in the genes of the UGE subset, we propose that Ahr is necessary for the regulation of PSC activity and that its over activation may impair self-renewal and the subsequent expansion and differentiation of prostate progenitor cells.
According to Marshall and Harrison [ 67], outcrowding may occur in two ways: "firstly, external incentives may impair self-determination, resulting in a shift in the locus of control and the resulting loss of professional autonomy.
On the contrary, if impulsive delay discounting is associated with impatience; i.e., simple aversion to waiting for delayed rewards (also referred to as "pure time preference"), subjects with greater delay discounting (e.g., substance abusers and ADHD patients) may have impaired self-control (e.g., impatience or impulsivity in psychiatry's sense, see Appendix I) [ 7, 14].
Already, only 48 hours after his arrival, it is evident that the Pope's visit will have a lasting effect on the whole Communist block and that it may impair the Kremlin's self-confidence at a time of leadership change in the Soviet Union.
MDD may impair type 2 diabetes self-care and increase physical inactivity and other behavioral risk factors such as smoking and obesity.
One explanation for this finding is that the cognitive behavioral changes (e.g., cognitive distortions, avoidance behavior, and attention deficits) associated with depression and depressive symptoms may impair patients' ability to recall self-care information.
Its main disadvantage is the high surface required for the initial layout of the self-rolling layers, which may impair yields or feasibility.
Along the same lines, not only inflammation may follow decreased AB clearance, but also defective autophagy-associated inflammation may impair the phagocytic ability of MECs, leading to a self-sustaining proinflammatory microenvironment.
We speculate that in BPD self-disgust is so heightened that it may impair the enjoyment of stimuli that are ordinarily considered as pleasant.
Although PIC is always self-limited and is not associated with severe debilitation or mortality, persistent cough may impair the quality of daily life [ 4].
This may impair recovery.
