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Although activity in these regions was not linked to variations in WM performance, these findings suggest a role of bottom-up sensory-driven mechanisms in the sensitivity to anxiety-inducing distracters, in which increased activity in perceptual areas may impair activity in brain regions responsible for active maintenance of goal relevant information.
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Previous studies suggested that HZ and PHN substantially impair health-related quality of life (HRQoL), that PHN may reduce the ability to maintain an independent lifestyle, and that acute and chronic HZ-related pain may impair activities of daily living, psychological well-being and social interactions [ 8– 13].
The oxidative damage that still occurred may impair the activity of more sensitive enzymes.
There is data indicating that some dietary supplements may impair the activity of anticancer drugs.
Mutations may impair Parkin activity, which might reduce the clearance and aggregation of proteins.
Furthermore, eccentric exercise may impair reflex activity which could lead to compromised joint stability during perturbations [ 43, 80].
For example, alpha-synuclein overexpression may impair mitochondrial activity, thereby accumulating mitochondrial DNA damage and degeneration, ultimately resulting in neuronal death [ 129].
TOR may impair sirtuin activity through the induction of the Pnc1p nicotinamidase via the transcription factors Msn2p and Msn4p, whose nuclear localization is inhibited by TORC1 signaling [ 74].
Given these expression results, we hypothesize that RDX may impair photosynthetic activity in zooxanthellae thereby affecting energy availability for the overall coral holobiont.
This may be because the cleavage sites responsible for generating the 32-kDa enamelin are not 100% conserved between pig and rat, and this may impair the activity of rat enamel proteases, such as MMP20, against the rat enamelin molecule.
In addition, the level of phospho (activated -BRCA1 decreactivated -BRCA15 in comparison with BAP1 WT cell lines (Fig. 5e), andecreasedductinn of phospho-BRCA1 may impair the activity of DNA repair.
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CEO of Professional Science Editing for Scientists @ prosciediting.com