The position of the microarray probe or MPSS signature within a given transcript may impact the measurement of transcript abundance due to the use of different polyadenylation sites or technical biases [ 26].
Indirect effects may be responsible for this unexpected result, based on changes in serum parameters and metabolism metabolites, which may impact on DEP-1 transcript levels leading to decreased DEP-1 activity in the skeletal muscle.
Additionally, molecular signatures in the 3′ untranslated region of maternally expressed transcripts may impact mRNA stability during the transcriptionally quiescent period following germinal vesicle breakdown and prior to the maternal to zygote transition.
Circadian expression profiles in secondary metabolism-related transcripts may impact on the progression of ripening and the final composition of berries, which could result in part from the cyclic expression of chief regulatory genes like VvMybA1, VvMybA3, VvMYBF1, VvMYB14 or a HY5 homolog.
The gene also harbors several CpG islands that when methylated may impact the expression of different transcripts.
Since intronic ESR1 DNA sequence variation may impact on splicing of ESR1 transcripts, we asked if three distinct SNPs, C25, C32 or C33, all in introns and preceding one of the two commonly spliced exons (5 and 7) were associated with detection of the Δ5 or Δ7 Esplicelice variants.
Given that FASX enhances expression of the secreted virulence factors streptokinase (Ska) and streptolysin S (SLS), and reduces expression of several extracellular matrix binding proteins, the variation in FASX transcript levels among clinical isolates may impact their virulence potential [15].
A total of 18 previously unreported SNVs and deletions that may impact the protein-coding potential of the CKM mRNA transcript were detected in 17 participants, eight enrolled in USA study sites, four in SA, and five in UGA.
A total of 22 previously unreported SNVs and deletions that may impact the protein-coding potential of the PKLR mRNA transcript were detected in 21 participants, 14 enrolled in USA study sites, four in SA, and three in UGA.
However, there is limited knowledge of the transcripts utilized by host and pathogen and how they may impact one another during this critical step.
