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We have shown that several of the new mutations we have found are closely related to known mutations involved in TSE diseases, while others may impact structural stability of the prion protein.
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During the insertion process the adhesive fills a very narrow gap over significant anchorage contact area, raising concerns that manufacturing defects may impact the structural performance of the bonded joint, namely the possible lack of adhesion resulting from inadequate preparation of the joint on site.
While association studies on schizophrenia show conflicting results regarding the importance of the regulator of the G-protein signaling 4 (Rgene gene, recent work suggests that RGS4 may impact on the structural and functional integrity of the prefrontal cortex.
Although participants with previous ADM use underwent a washout period prior to participating in the study, the long-term impacts of ADM use on brain structural features that may impact on remission are not well understood.
However, a comprehensive application of ecological systems theory to school bullying, (Hong & Espelage, 2012) moves beyond the investigation of such associations, identifying a more significant role for structural inequality which may impact also at other levels.
Finally, a comparative study between different hospitals may provide valuable insights into how structural organization and procedural management may impact the contact patterns among individuals, and therefore the potential epidemic spreading within the hospital.
Structural issues in residential care may impact on the way that care is delivered.
In addition, A βo binds to membranes directly which appear to involve GM1 ganglioside and as such are thought to induce structural and functional changes which may impact Ca2+ signalling and synaptic plasticity [ 20, 21].
In conclusion, changes in mechanical and structural properties of decellularized leaflets were likely associated with disruption of the ECM, which may impact the durability of the leaflets.
The aim of this study was to assess numerical alterations and structural rearrangements of Chr17 in breast cancer cells and to elucidate how these alterations may impact on the HER2/CEP17 FISH results on interphase nuclei.
Structural antecedents such as SES influence both exposure to and ease of obtaining information, which may impact how information is accessed, accepted, processed, and used.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com