Sentence examples for may impact efficacy from inspiring English sources

This analysis is particularly relevant for anti-IGF therapy as there are multiple approaches in clinical trials and results from these trials suggest that variability in the levels of different IGF system components between patients may impact efficacy [ 53],[ 55].

However, ideally these approaches should be applied in an integrated fashion to allow for their interaction, as toxicity-induced dose reductions may potentially impact efficacy.

To assess the use of oral glucose tolerance testing (OGTT) to predict efficacy of insulin sensitization (metformin) or suppression (octreotide) because insulin resistance and insulin hypersecretion may impact pharmacotherapeutic efficacy in obese children.

This allowed judgement to be made on the nature of the new regulatory system and on the constraints that may impact its efficacy following implementation.

In this chapter, we describe emerging strategies for EV engineering and consider how different approaches to EV production, purification, and design may impact the efficacy of EV-based therapeutics.

Additional factors that may impact microbicide efficacy are sexual activity and semen.

The selection and spreading of CTL-escape mutations may impact the efficacy of immune response at a population-level, whether it is natural[11], [12] or intended to be stimulated through vaccination [13], [14], [15].

Furthermore, it may impact the efficacy of a second-line antiretroviral therapy regimen in Nigeria [ 28].

Also, increasing resistance of Anopheles mosquitoes to insecticides may impact the efficacy of malaria control [ 9].

These variants may impact the efficacy of the drugs they metabolize.

Chemotherapy-induced immune depression may impact the efficacy of vaccinations in children.