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This effect may, however confer some specificity, and some proteins are directly redox regulated, such as ion channels, p53, and aconitase, either by the thiol mechanism or by changes in the oxidation-reduction state of iron or other transition metals [ 33].
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These mutations, however, confer resistance to EGFR inhibitors.
That the Mirra server is an independent element of a network, however, confers some benefits.
However, CR may confer other benefits independent of autophagy.
However, it may confer some unusual thermal and acidosis stability to the globin fold [ 59, 60], which could be relevant under environmental or cellular stress.
However, TP53 may also confer PDT resistance to cells, possibly through DNA repair mechanisms, as cells allowed to recover for 24 h had similar clonogenic potential as the TP53-deficient cells.
The high cost of the rich club may, however, be offset by significant functional benefits that the rich club confers to the brain network as a whole.
However, because this may not confer lifelong immunity, booster shots of the vaccine are recommended every 10 years.
The relatively low level of expression of the "2.5 kb" construct suggests, however, that this fragment may confer instability of the fusion transcript; this may result in less apparent further destabilization by the shRNA expression constructs.
However, BRAF-inhibitor resistance mechanisms may also confer resistance to MEK-inhibitor and combined therapy.,, The resistance may be associated with MAPK and S6 kinase activation.
Little is known, however, regarding medical conditions that may also confer susceptibility, such as diabetes or chronic obstructive pulmonary disease (COPD).
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CEO of Professional Science Editing for Scientists @ prosciediting.com