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Thus, a decrease in extracellular PPi may hinder normal bone remodeling, for instance, by inhibiting osteoclast differentiation or activity.
Further, excess delivery of therapeutic agents may create a competitive problem to some other biomolecules that may hinder normal functions of cells, cellular organelles, enzymes, and signaling molecules.
Overstabilization of interactions between pathogenic WDR73 fragments and tubulins may hinder normal movement of WDR73 along mitotic microtubules, slow spindle microtuble dynamics (Colin et al., 2014), and/or slow the large amount of protein and vesicular trafficking along mitotic microtubules during cell cycle (Hu et al., 2012; Agromayor and Martin-Serrano, 2013; Green et al., 2013).
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Epigenetic markers may likewise hinder normal development: the offspring of parents who experience famine are at heightened risk for developing schizophrenia, some research suggests — perhaps because of the chemical signatures on the genes that parents pass on.
Mutations may permanently hinder normal folding and in this case the risk of pathology increases as the unfolded proteins accumulate in the tissues causing aggregation and formation of insoluble fibrils and plaques [27].
The doctor may also test for other conditions that hinder normal blood pressure, especially if the patient is already on medication.
It is worth noting, however, that this database periodically requires a compaction step which may hinder system performance, but which does not affect the availability of its nodes under normal operation [3].
That may hinder efforts to restore a species.
"But the lack of money may hinder things".
That may hinder rather than help the fight against terrorism.
The World Health Organisation says closures may hinder travel and trade without detecting cases.
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CEO of Professional Science Editing for Scientists @ prosciediting.com