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It may help to place these numbers in historical perspective.
The binding of ligand to these targets can be substantially distinct from other target types since such metal ions often coordinate ligand polar atoms, which may help to place and orient the ligand correctly in the binding sites.
Here, I just want to comment that, in general, a more thorough discussion of the literature on the role of energy in biochemical systems may help to place the theoretical result more solidly as novel, if the authors feel they can do it without pulling focus from their discussion of the chaperone system.
Given that the VC in high SCI is influenced by the position of the patient (the diaphragm tends to remain partially collapsed due to the effect of gravity), it may help to place an abdominal girdle, which can improve respiratory function in the sitting position by placing the diaphragm in a more efficient position.
3) [… In] general, a more thorough discussion of the literature on the role of energy in biochemical systems may help to place the theoretical result more solidly as novel, if the authors feel they can do it without pulling focus from their discussion of the chaperone system.
Further analysis, including searches of updated databases, more sensitive ortholog definition, and perhaps inclusion of additional molecular and morphological characters, may help to place many of these singletons on the tree, as well as to lend better statistical support to the internal branches.
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In case of suspicion of obstruction, however, it may help to localise the place and extent of the obstruction.
It may also help to place the kitten's food bowl where the litter box used to be, as most cats are reticent to use the toilet where they eat.
The hospitalist model may be one approach which helps to place physicians and other health care providers together to engage in mutually advantageous communication, which can result in increased provider satisfaction, collaboration, and high quality patient care.
Passive clinician consent may help to reduce the burden placed on clinicians and has been used successfully by a number of international registries and studies [ 12, 13].
It may help to use an elevated place or table.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com