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Exact(14)

Nevertheless, in a subgroup of patients, the presence of a deleterious mutation may have phenotypic consequences.

These nonsyn-SNPs may have phenotypic effects on the pathogenicity of K. pneumoniae, and are thus worth further functional evaluation.

Moreover, such DNA methylation changes may have phenotypic consequences as illustrated by the association between higher IGF2 methylation and decreased birth weight.

However, some persisting MCS variants may have phenotypic effects that influence disease risk.

The individual now carries a null genotype at that locus, which may have phenotypic consequences.

It seems that c-Kit+ cells may have phenotypic and functional features of cardiac-specific mesenchymal cells [ 11].

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Similar(46)

It has, however, been argued that only a subset of X-linked genes, in particular those that are involved in large protein complexes, need to be dosage compensated [ 2]; and similarly, a lack of dosage compensation for those genes that escape from XCI may only have phenotypic consequences for a subset of genes.

Although hybridization increased phenotypic variation and heritability of age at first flower in our study, and thus increased their evolutionary potential, hybridization also may have constrained phenotypic evolution by increasing phenotypic correlations and producing life-history trade-offs.

Apart from population structure, a major challenge for GWAS is genetic heterogeneity, whereby different alleles at the same locus may have similar phenotypic effects48,49.

These findings are intriguing and suggest that monocytes, within a sub-classification system, may have alternative phenotypic signatures in response to inflammation.

By insertion, they can cause a genetic change that may have a phenotypic effect, for example when by insertion they introduce a regulatory element or impair one, thereby changing when and in which cells a certain gene is expressed.

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