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In the clinic, the relevance of CTCs as a predictive biomarker may have maximal value in a pre-treatment setting.
Pharmacotherapy for recovery from aphasia when delivered in combination with behavioural training (Berthier et al., 2009) may have maximal potential when also combined with tDCS.
Those efforts may have maximal scientific and practical influence if new findings are placed in context of the well-understood lifestyle and reproductive risk factors or existing risk prediction models for breast cancer.
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We call this zero maximal if κ is (among all other zeros of Q maximal in the modulus and if multiplicities of other possible zeros of Q having the maximal modulus do not exceed m κ. Of course, Q may have several maximal zeros (with the same modulus and multiplicity).
Interestingly, we will show that problem (1) may have minimal (maximal) solutions between given lower and upper solutions and not have the least (greatest) solution.
We speculate that Tregs may have a maximal suppressive activity; IL-2/anti-IL-2 mAb treatment may not be able to further improve Treg's inhibitory activity when Tregs were already very potent during the stimulation phase.
Mean times of migration at the three nuclear genes indicated that gene exchanges are probably not recent and may have been maximal ~20 000 to 300 000 years ago and support the hypothesis of incomplete lineage sorting and ancestral variation [see [ 49, 70]], favouring an increasingly stronger barrier scenario.
For this reason, to rank users who have maximal belief mass on the same degree (for example, two users who have the degree V.Strong as a maximal degree), we should not consider the mass they have on this degree, because we may have a user more influential than another, although he has a weaker belief mass than him on the same degree.
This may imply that ketamine may have larger half maximal inhibitory (ID50) when compared to the other two; however, it needs further investigations.
We speculate that this may be attributed to the abundant expression levels of miR-1246 in these HCC cell lines and that regulation of target genes by miR-1246 may have reached the maximal extent.
The regulatory effects of miR-1246 on CADM1 may have reached the maximal extent due to the relatively high expression of miR-1246 even before the transfection of miR-1246 mimic.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com