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Other recent studies lend further support to the idea that defects in protein clearance mechanisms (proteolysis or autophagy) may have integral roles in ALS.
Although basic science research suggests that vitamin D may have integral roles in the optimal functioning of the immune system, it is not clear whether correction of vitamin D depletion or optimization of vitamin D status or both are efficacious as an adjunctive therapy in the prevention or treatment of infection, particularly in critical care.
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Another implication was that the positive feedback created by temperature-dependent conductivities may have been integral to the differentiation of the Earth into core, mantle, and crust from its original chrondritic (meteorite-derived) composition.
Historically these systems may have been integral to the formation of opal, bauxite, some low temperature ore deposits, of authigenic K-feldspars, and continental redbeds.
This may have been integral for display and flight, but this remains unknown at present.
Therefore, larger apoptotic trophoblast debris may have an integral role in tolerizing maternal immune cells to fetal alloantigens.
Altogether, this suggests that EPLIN may have an integral role in cytokinesis and loss may lead to aneuploidy and genomic instability of daughter cells [ 41].
You will find tarps that have integral snaps that secure them, or you may want to anchor your tarp with bungee cords, which can be lapped over the sides of your truck's bed and hooked under the fenders.
The open impeller design may have vanes cast integral with the hub, usually without side walls.
Another Guodian document, given the title "Taiyi shengshui" ("The Great One Gives Birth to the Waters," translated in Ames and Hall 2003; also see Boltz 1999 and Allan 2003) and which may have formed an integral part of the Guodian Laozi "C" text, certainly reflects strong interest in cosmogony and cosmology.
Further, while SRH services, in particular family planning (FP) and maternal and child health (MCH), may have been considered integral components of a generalist primary health care (PHC) structure, treatment-focused HIV services have often been delivered within more specialist units in tertiary health facilities, or by health workers with a sub-specialism in HIV [ 5, 6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com