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Exact(7)

We also observed that CTL with this specificity were not detectable in HLA-A2 positive humans, which was compatible with the suggestion that tolerance mechanisms may have inactivated or deleted such CTL.

The conserved long open reading frame in the PEG11 gene indicates that there is an evolutionary requirement to maintain the encoded functional protein domains even though mutations to key residues in some of these domains may have inactivated their catalytic functions.

Storage in higher temperatures may have inactivated the virus.

It is also likely that enhanced ROS may have inactivated Atg4 and consequently promoted LC3B lipidation to induce autophagy.

Cell culture analysis showed no culturable virus; chlorination of the wells before sampling may have inactivated the viruses.

However, we found no evidence of replicating virus in the saliva samples (8, 9 ); neutralizing antibodies or salivary components may have inactivated the virus.

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Similar(53)

In the calculations we have excluded the option that, in XaXi cells that just have inactivated an X chromosome, the active second X chromosome may still have a probability to be inactivated.

Since we have inactivated γ-secretase by deleting the Presenilin genes, one or both of the above functions may reflect a protease-independent activity of presenilin [94], [95].

The agents are genetically altered viruses that will grow only in cells that have inactivated their p53 or Rb proteins.

Onyx-015 attacks cells whose p53 protein is inactive, and another virus, Onyx-411, is designed to flourish in cells that have inactivated their Rb gene.

Tumor cells have inactivated p53.

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