Patients with a large pleural effusion and right ventricular diastolic collapse may not have hemodynamic compromise; however, early ED thoracentesis can improve patients' symptoms [4].
This is illustrative of the disproportionate increases in RR to maintain alveolar ventilation at progressively lower VTs, especially when close to the dead space, and the need to increase Pmean, which may have deleterious hemodynamic effects.
This report makes 2 important points: (1) pannus overgrowth may be a favorable determinant of the durability of xenografts, and (2) bovine pericardial valves may have excellent hemodynamic performance and tissue durability for more than 20 years in the mitral position even in young patients.
Aggressive fluid loading as recommended in septic states may have worsened hemodynamic and respiratory conditions in the ICU group.
This is important in that MEG/EEG and fMRI data are likely to have different sensitivities to certain source configurations: for example, sources deep in the brain (far from the sensors) are likely to be represented only weakly in the MEG/EEG data, whereas very transient source activity may have minimal hemodynamic correlates [see, e.g., Nunez and Silberstein, 2000, for further discussion].
Furthermore, if a long delay to sternal closure and a long duration of RRT were considered markers of hemodynamic impairment, then switching to HFOV may have resulted in hemodynamic improvement in the present cohort, since both the delay to sternal closure and the duration of RRT were slightly reduced in the HFOV group (Table 1).
In this rather small study, including 121 patients only, 61 receiving rtPA, the authors did not observe any major bleeding complication, suggesting that lower dosage of thrombolytic treatment may have a significant hemodynamic impact without increasing the risk of major bleeding.
A final limitation of our study is the intravenous mode of terbutaline administration which may have provoked more hemodynamic effects than other routes.
This value may have been affected by hemodynamic or metabolic status.
Therefore, it seems that chronic exposure to thyroid hormones may have more long-lasting hemodynamic changes [ 18, 19].
