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One or more common ancestors to the Kinetoplastida duplicated each of XPO7, IPO8 and also may have duplicated IMB2 (Figure S2 d, e, f)).
These five SERK genes in Medicago may have duplicated since it diverged from Lotus.
In the case of CD46A and CD46B, we speculate that the two snoRNA gene isoforms may have duplicated and diverged before the emergence of RIP.
This ancestral cA-SR may have duplicated into 2 distinct proteins (labelled 1.1 and 1.2) which would have contained the domain structure typical of this group (i.e. cytoplasmic, transmembrane, collagenous, and C-terminal domains).
As NDN is a maternally imprinted gene, it is feasible that LUCC6 may have duplicated the silenced allele giving a hypermethylated result, yet still contain an unmethylated paternal allele from which the protein is expressed.
The predicted gene in Lotus which appears to be orthologous to the five SERK3/4/5 family member genes is a single copy gene, indicating that the Medicago genes may have duplicated after the divergence of Medicago and Lotus.
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Genes within a particular co-duplicated group share the same evolutionary history and duplicated in concert with each other, while the genes belonging to different co-duplicated groups may not share the evolutionary history and may not have duplicated simultaneously.
The distinct genes within each co-duplicated group share the same evolutionary history and are duplicated in concert with each other, while the constituent genes of two different co-duplicated groups may not share their evolutionary history and may not have duplicated simultaneously.
It has been shown that genes within each of these co-duplicated groups (of HOX cluster paralogons) are duplicated in concert with each other whereas the constituent genes of two different co-duplicated groups may not have duplicated simultaneously [ 17].
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