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Cystic pancreatic neoplasms range from benign to malignant, and although they may have diagnostic features on CT, often other techniques such as ultrasound and MRI are required for further evaluation.
"They may have time aspects to them, they may have diagnostic aspects to them, they may have classification aspects to them, they may have judgement, decision making aspects to them.
Given that 90Y microsphere dosage is based upon the pre-therapy 99mTc MAA LSF and that MAA particles are more variable in size (e.g., 10-90 microns) than 90Y microspheres 20-355 microns), quantitative estimation of the post-therapy 90Y microsphere LSF using dPET/CT approaches may have diagnostic and therapeutic impact by identifying patients with smaller or larger than anticipated LSFs.
Therefore, it is reasonable to speculate that tissues with more sites of allelic imbalance have a greater likelihood of having disruption of any of the numerous critical genes that cause a cancerous phenotype and thus may have diagnostic or prognostic significance.
Lung carcinoma development is accompanied by field changes that may have diagnostic significance.
Thus, characteristic peak clusters can reliably differentiate tumor groups from placebo groups and may have diagnostic potential.
In all cases, increased variability in expression levels would facilitate reaching of the critical "triggering" parameters, thus its direct measurement may have diagnostic and prognostic value.
Recent studies have shown that urine LAM may have diagnostic value in HIV-infected [15], [16], [17], [18] but not in HIV-uninfected TB suspects [19].
The levels of IP-10 in unstimulated blood of LTBI patients may have diagnostic and prognostic value for further investigation, and higher levels may indicate a potentially protective mechanism for the development of LTBI rather than active TB.
Lacunarity was shown to exhibit higher values in melanoma compared with non-melanoma [18], and it has been proposed that lacunarity may have diagnostic utility as an independent parameter in melanoma diagnosis if combined with mean diameter and range of blue [14].
This knowledge, in conjunction with the fact that the trancriptome of peripheral blood mononuclear cells has been shown to be altered in the context of many diseases, including renal cell carcinoma, lead us to study if any such alteration in gene expression exists in PC as it may have diagnostic utility.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com