In addition to the head (H), the NP may also have determinant(s) (DET) and/or modifier(s) (MOD).
Differences in the genetic architecture of individuals may have affected determinant pathways in different ways.
During the pandemic (H1N1) 2009 outbreak, severe pneumonia developed in young adults who had no identifiable risk factors; early diagnosis and treatment of influenza virus infections may have a determinant role in outcome.
However, because autophagy appears to become markedly induced in the presence of all-trans retinoic acid and arsenic trioxide, this degradation pathway may have a determinant role in therapy-induced PML/RARa clearance.
Preeclampsia, gestational hypertension, and unexplained intrauterine growth restriction may have similar determinants and consequences.
These may have different determinants.
Furthermore, different settings may have differing determinants of facility delivery, limiting the generalizability of our findings.
DA, like PMD, is positively associated with breast cancer risk and may have genetic determinants that are not shared with the non-dense area of the breast.
Interindividual variations in metabolic rate and in the thermic effect of food are important determinants of caloric expenditure, and an increasingly recognized factor, nonexercise activity thermogenesis (39), which includes activities like "fidgeting," may have genetic determinants as well.
However, this does not imply that these factors should be combined in measurement tools, especially since these disorders may have different determinants and/or outcomes, and they may require different treatment strategies [ 53].
