Sentence examples for may guide dose from inspiring English sources

Pharmacokinetic estimates for intravenous paracetamol in individual adult cohorts are different to a certain extent, and understanding the covariates of these differences may guide dose individualization.

Using biomarkers to drive tumor growth inhibition enables a quantitative assessment of the relationship between biomarker and tumor growth inhibition, which may guide dose regimen selection in the clinic if similar biomarker data can be obtained.

This will facilitate future studies of this agent in addition to providing information that may guide dosing for patients individually.

The negative results from these large expensive trials have led many to reassess the design of clinical chemoprevention studies and to move towards smaller studies focussing on higher-risk individuals, and to rely on more detailed prior preclinical mechanistic evaluation to provide information that may better guide dose selection.

The developed survival model may guide intrapatient dose escalation based on dBP and neutropenia and explore the effectiveness of alternate dosing strategies.

Thus, population-based approaches are often the best option and can identify covariates that may be useful to guide dose individualization.

Molecular functional imaging may guide individual treatment doses, thereby decreasing drug toxicity side effects or avoiding ineffective treatments in drug-resistant tumours and reducing economic health costs of potentially ineffective therapy in individual patients.

The authors believe that further investigation of such factors, which may significantly differ among individuals of similar weight, cross-sectional area and BMI [10], may guide future methods of dose optimisation in abdominopelvic CT and may allow radiologists to refine examination technique and ATCM protocol particularly in obese patients.

Optimized antibiotic dosing may help reduce this burden; however, data to guide dosing in patients with severe sepsis/septic shock and multiple organ dysfunction under CRRT are scant.

Adjustment of antimalarial dosing may be necessary to avoid toxicity, but adequate data to guide dosing adjustments are under investigation and not yet available.

14 ICUs (52%) had no specific protocols to guide dosing for patients undergoing RRT. 10 ICUs (37%) dosed these patients with a defined dose per kilogram (ranging from 3 to 7mg/kg) and then used trough levels to guide re-dosing.