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Bringing a disparate group of retail and investment banks under one roof may generate resistance.
It is generally believed that low doses of TRAIL induce a poor apoptotic response and may generate resistance, whereas exposure to high levels of this cytokine results in extensive cell death, indicating the existence of a cellular threshold for triggering apoptosis (referred hereafter as 'sensitivity'sensitivity
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Mutations or fusions of both EGFR and ALK may be primary causes of cancer, whereas both the EGFR gatekeeper mutant T190M and MET may generate drug resistance.
Mechanistically, these elevated cytokines may generate glucocorticoid resistance, perhaps by interfering with glucocorticoid receptor translocation [ 62, 63], and thus leading to chronically elevated plasma cortisol associated with the depressive state.
And they use coercive measures that generate resistance.
When Shoulds run governments, they generate resistance and their problems don't get solved.
However, genotypic tools for the detection of antimicrobial resistance may generate false negative results due to (i) their inability to detect new resistance mechanisms or (ii) false-positive results, because they may detect inactive or incomplete resistance genes in a specimen, which have not inferred resistance to the antimicrobial drug under test [ 37].
These constraints combined with the substantial fitness cost of lacking resistance to antibiotic-producers may generate stabilizing selection that favors Streptomyces with moderate resistance capacities rather than those having very few or very many antibiotic resistances.
In fact, it may generate even more inspirational tales of resistance.
This provides a potential novel resistance signal, which, when targeted, may generate more effective inhibition of cell growth compared to IGF-IR treatment alone.
In addition, it should be noted that decisions to allow a period of time for civil servants to 'test' the benefits of a programme before they start making contributions may be difficult to reverse and may become a reference point that generates resistance amongst prospective contributors.
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