Otherwise, the tocopheroxyl radical can react with lipids to generate lipid radicals.
57 58 Alternatively, fatty acids may be transported intracellularly and metabolised to generate lipid intermediates including ceramides and diacylglycerol.
As an important biomolecule, lipid can be easily attacked by ROS to generate lipid peroxidation which is harmful to cell.
Iron loading may reduce endothelium-derived nitric oxide directly by decreasing endothelial and inducible nitric oxide activity [ 25], and indirectly by stimulating membrane lipid peroxidation to generate lipid peroxyl radicals [ 26].
Thus, COX-2 oxygenation of 2-AG and AEA may lower cannabinoid tone by reducing the concentrations of endocannabinoids and may generate new bioactive lipids by increasing the concentrations of PG esters and amides.
For instance, oxidative stress can induce enhanced metabolism of fat molecules (i.e., lipid peroxidation) that may generate biologically active molecules.
Transition ions (ferrous iron) may generate highly reactive free radicals which can initiate the process of lipid peroxidation [ 16].
However, exposure to reactive oxygen and nitrogen species (RONS) may cause lipid peroxidation in cell membranes, which in turn may generate species that damage cell proteins and promote their degradation [ 11].
In DM, protein glycation, mitochondrial dysfunction, and glucose autoxidation may generate free radicals, which mediate damage to cell structures, including lipids, membranes, proteins, DNA, and disrupt cellular integrity [ 8].
Shale gas may generate taxes.
