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These values are almost comparable to the corresponding values for intermolecular π⋯π interactions, showing that π⋯π contacts may further stabilize the structure.
The inter-chain C H···Cl hydrogen bonds between the pyridine rings and the coordinated chloride anions extend these 1-D coordination frameworks to result in a novel 2-D supramolecular architecture, and there exist significant edge-to-edge π π stacking interactions between the inter-chain neighboring pyridyl rings of the ligand, which may further stabilize this structure.
There is also a detectably direct interaction between M and N proteins in the nucleocapsid, which may further stabilize the M-genomic RNA interaction [11].
Hydrophobic residues on helix H1 interacted extensively with non-polar side-chains on helix H12, which may further stabilize the relative position of helix H1 and helix H12.
This suggests that doxorubicin stabilizes wt p53 protein and may further stabilize p53 14/19.
Such interactions may further stabilize the apex of the cone formed by the five MA helices.
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Thus, the binding of ligands to the SH2 and SH3 domains has been proposed to displace intramolecular interactions and to favor an active conformation that may be further stabilized by phosphorylation of the activatory tyrosine [13], [14].
This confirmation may be further stabilized by the presence of a DNA binding region immediately upstream of τ500 (marked with '2') (Jergic et al., 2007).
Tetramerization of the recombinant RyR N-terminal domain is primarily mediated by non-covalent protein protein interactions, which may be further stabilized by covalent disulfide bonds.
As the acquisition process in OCT is much faster than in ultrasound and the scanning location may be further stabilized by the use of an eye tracker or software motion-artifact correction, we can assume no motion at all.
This conformation may be further stabilized by the presence of a DNA binding region immediately upstream of τ500 (indicated with '2'; see text for more details).Upon encounter of a release trigger, the contact between τ500 and the polymerase fingers domain is restored (indicated with '3'), and the contact between the clamp and polymerase tail is broken (indicated with '4').
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