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Thus the synthesis of RvE1 by Candida, resident on the host mucosa in small numbers as a commensal organism, may functionally sequester the fungus from host innate surveillance.
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Cav1 may function to sequester critical effectors that regulate the raft-dependent endocytosis of AMF/PGI [50].
A key event in the disruption of the autophagy pathway in CF airways is the formation of insoluble, HDAC6 positive aggresomes that functionally sequester the BECN1 PtdIns3K complex.
Nuclear inclusions may serve a similar function, sequestering aggregation-prone polypeptides into relatively inert higher-order complexes.
This suggests that this double-mutant BCL9 may sequester a functionally important ligand other than β-catenin and Pygo (see below).
Cytoplasmic YAP may directly sequester β-catenin in the cytoplasm or cytoplasmic TAZ may sequester DVL2 impeding its activity to promote β-catenin accumulation in response to Wnt stimulation [ 90, 91].
The immunoglobulins may also sequester certain activated complement components and block the activity of F c receptors.
Luna, J. M. et al. Hepatitis C virus RNA functionally sequesters miR-122.
Necrotic bone may be replaced without any clinical implications or may sequester if infection is present [ 42].
Ro60 and/or La may sequester Y RNAs and prevent them from functioning in chromosomal DNA replication.
The process of bacterial sulfate reduction may coprecipitate and sequester As, a mechanism that is unlikely to occur in Type II groundwater.
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