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This observation suggests that SIRPα may function to decrease transendothelial migration of monocytes or other circulating leukocytes, reduce the burden of inflammatory cells in atheroma, and ultimately decrease plaque mass under atherogenic conditions.
Indeed, in humans EE2 is known to be a mechanism-based inactivator of the key CYP3A isoform CYP3A4, which may function to decrease EE2 metabolism because CYP3A4 is the main enzyme involved in EE2 oxidation (Lin et al. 2002).
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RKIP is not thought to alter the tumorigenic properties of PC cells, rather it is thought to be a suppressor of metastasis and may function by decreasing vascular invasion [ 20].
We conclude from this that epithelial cell invasion by Salmonella is not sufficient to produce diarrhea in this model, though it may transiently impair epithelial cell function enough to decrease net water absorption.
NDRG2 and GLUT1 were inversely regulated by p53 [ 4, 33] and Myc [ 35, 37], which suggests that NDRG2 may function as a tumour suppressor by decreasing glucose uptake.
Therefore, heart diseases may lead to decreased function of warm, presenting chilly or cold limb, soreness and weakness of waist and knees and night-time frequency or nocturia.
This suggests that referral coordinators may function differently with different kinds of patients, decreasing overall transfer rates but facilitating within-system transfer when transfer occurred.
In addition to muscle atrophy, other factors may contribute to decreased muscle function.
Thus, AGE accumulation may contribute to decreased muscle function with aging through a variety of mechanisms.
Decrease in fast-shortening-velocity isoform (α-MHC) coupled with increases low-shortening-velocity isoform (β-MHC) may contribute to decreased contractile function [ 17].
Among Wnt antagonists, murine models revealed that Dickkopf and secreted Frizzled-related proteins are upregulated in arthritic synovial tissues and may contribute to decreased osteoblast function [ 14].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com