Sentence examples for may function directly from inspiring English sources

Depression symptoms may function directly to promote weight gain through a physiologic mechanism.

This expression pattern suggests that TADG-15 may be important in establishing primary ovarian tumours and it later may function directly or indirectly as a progression inhibitor.

Analysis of gene annotation data reveals that PLCD1 is a phospholipase C homologue that may function directly downstream of GNA11 (Table 1).

Several recent publications shed light on this topic and suggested that HDAC may function directly at sites of DNA damage by altering local histone code (Miller et al, 2010; Robert et al, 2011).

Translesion polymerases may function directly at the replication fork (Friedberg, 2005), or may fill in postreplication gaps containing lesions that are left behind by replication forks (Lopes et al, 2006; Callegari et al, 2010).

In addition, some autophagy proteins may function directly as a pro-apoptotic factor to initiate apoptosis, such as a calpain cleavage product of Atg5 and the unconjugated form of Atg12.

The new insight into regulation of Nrf2 explains multiple features unexplained by the conventional mechanism: activation occurs without change in Nrf2 protein concentration, Nrf2 transactivational activity is inhibited by prolonged nuclear residence time (73) and potent activators of Nrf2 may function without directly binding to Nrf2 or Keap1 (54).

Alternatively, TRPV4 channels may not function directly as the mechanosensor, rather as critical components of down-stream signaling (reviewed in Liedtke and Kim 2005).

Besides facilitating entry into the vasculature, some bacterial adhesins may also function directly in resisting complement-mediated killing.

Third, inhibition of TOR may regulate mitochondrial function directly and thereby control ROS production, since TOR has been reported to localize in mitochondria [43].

Although recent studies suggest that kinases may regulate proteasome function directly, we did not find any physical association between εPKC and the proteasome.