Exact(1)
Collectively, the above studies may suggest that, opposite to class I HDAC isoforms, increasing the expression of class IIa isoforms may facilitate specific forms of learning and possibly also CBT-based fear extinction; however, this remains to be tested.
Similar(59)
Targeting LMP1 and other factors, such as LMP2A, may facilitate effective, specific drug development for the treatment of CAEBV.
It is conceivable that these ncRNAs may facilitate the specific expression of DLGAP4 mRNA isoform a in Purkinje neurons of the brain by recruiting chromatin-modifying factors and/or transcription factors (51).
As another antiterminator of the BglG family (BvrA), which is only present in lineage II isolates [ 50], has been shown to be involved in cellobiose-dependent repression of PrfA-dependent virulence genes in L. monocytogenes [ 91], lmo0297 may have evolved to facilitate specific transcriptional repression functions in lineage II.
As CRISPRi employs a genetically encoded catalytically inactive Cas9 nuclease (dCas9 47, we postulated that co-expressing dCas9 under the control of a tissue-specific promoter and gene targeting sgRNAs may facilitate tissue-specific knockdown of tmem33.
Eventually, EHMs may facilitate patient-specific organ transplantation via in vitro generation of partial or whole-organ structures.
The expression of FOLR1 cannot be observed in normal endometrium tissue [ 67], suggesting that FOLR1 may serve as a good tumor cell surface marker for targeted therapy, and antibodies against FOLR1 may facilitate tumor-specific cellular uptake of molecular drugs.
A protocol may be implemented by the use of a checklist, and can be used to facilitate specific treatment guidelines.
Concurrently, interventions aimed more generally at improving prefrontal cortex functions, such as working-memory training, may facilitate the more specific interventions because these general functions play a part in alcohol-specific regulation functions.
The observed differences in kinetic properties of BmHk as compared to host enzyme may facilitate designing of specific inhibitors against BmHk.
The observed differences in kinetic properties of P. yoelii ADA as compared to the erythrocyte enzyme may facilitate in designing specific inhibitors against ADA.
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