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The ensuing alteration in chromosome architecture and transcription may facilitate pathways that maintain genomic stability, or prevent epigenetic alterations, and therefore retard some aspects of the aging process in the long-term.
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These approaches may facilitate pathway engineering for biofuel and biochemical production.
Maintaining high levels of the HRQoL, especially in these subgroups, may facilitate clinical pathways for healing and acceptance of the disease.
50 genes were predicted to encode proteins with modifying (methylation; glucosyl or glutathione transferase) or hydrolytic activities against proteins and carbohydrates, including peptidoglycan deacetylase and lytic transglycosylase activities which may facilitate new pathways of cell wall growth.
Our results also suggest that increased Ku-70 level may facilitate NHEJ pathway of DSB repair in high glycolytic cells leading to reduced micronuclei and increased cell survival against radiation.
The KEGG pathway analysis based on the proteomic data indicates that up-regulation of cytoskeleton related pathways may facilitate migration of MCF-7-TamR cells.
Characterization of these export pathways may facilitate the identification of novel drug or vaccine targets.
We hypothesized that these signaling pathways may facilitate resistance.
Careful analysis of these signalling pathways may facilitate the development of targeted therapies.
However, we have previously shown improved survival associated with tumours with increased immune infiltration [ 47] and the activation of specific secretory senescence pathways may facilitate this.
Similarly, it has been suggested that defects of recombinational/repair pathways may facilitate acquisition of additional cytogenetic abnormalities in CML [ 9, 10].
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