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The existence of the S-state neamine may facilitate binding of neamine-like aminoglycosides by favorable entropy of binding to the A-site of 16S ribosomal RNA, suggesting that novel aminoglycoside compounds carrying a S-state neamine pharmacophore can be developed.
Thereby, tBRD-1 may facilitate binding of tTAFs to the promoters of certain genes relevant for spermatid differentiation.
In addition to information about when to listen, timing may be important for another reason: temporal coherence may facilitate binding of auditory and visual stimuli into single cross-modal objects.
Furthermore, products of one or more of these genes may facilitate binding to transferrins/lactoferrins of different host species and such a gene repertoire could enhance the ability of this bacterium to survive in a variety of ruminants.
Overall, the data suggest that Opa binding to the receptor requires an extended aliphatic chain at position 91 and certain arrangements of the chain may facilitate binding of most Opa proteins (Ile = leu > Thr).
The more recognizable candidates for conjugative processes are listed in table 2. PspC-like proteins can be involved in cell wall binding, so may facilitate binding of the conjugation pilus.
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The oligomerization of Rev-like proteins in other retroviruses may similarly facilitate binding to existing Crm1 orthologs that lack the dimeric interface.
Therefore, SFN-mediated demethylation of CpGs of the CTCF binding sites may facilitate the binding of CTCF to the hTERT gene regulatory region to allow for CTCF-mediated down-regulation of hTERT expression in MCF-7 and MDA-MB-231 cells.
The hydrophobic character of the regions near the substrate-binding groove may facilitate the binding of hydrophobic polymeric substrates.
In order to confirm whether correct N-glycosylation of CD62L may facilitate Treg binding to HEV, we assessed the ability of Treg and TregKIF to bind axilliary LN sections in a modified Stamper Woodruff assay [30].
The ability of TregKIF to bind to ICAM-1 was reduced suggesting that correct N-glycosylation of LFA-1 may facilitate Treg binding to ICAM-1.
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