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The total effect of mistranslation could be even stronger because misfolded proteins may expose normally buried residues that seek the nonpolar surfaces of other misfolded proteins, promoting cytotoxicity through protein aggregation (Bucciantini et al. 2002).
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Monomers in excess can also expose normally buried degradation signals, which can lead to their efficient degradation [ 10].
These results exemplify that meprinβ may distribute all over the cell surface upon loss of cell polarization, which may expose additional substrates that normally would be inaccessible to the protease.
It has been demonstrated that the histone hyperacetylation induced by HDAC inhibitors causes structural alterations in chromatin, which may expose portions of DNA that are normally protected by heterochromatin to DNA-damaging agents, such as UV, cytotoxic drugs or ROS.
The result can be explained on the basis that a farmer with large farm size normally takes more time to apply pesticides; hence, it is believed that the effect of spraying without PPE may expose him/her to the harmful effect of the chemicals.
It may expose you to abuse.
Wilson said the gun bill may expose security flaws.
Not paying an intern may expose you to significant risk.
This may expose some unstained areas.
But one tipping point may just expose the next.
Exposed animals may perform normally under some test conditions (e.g. frequent reinforcement), but abnormally under others (infrequent reinforcement), adding to the argument that neurobehavioral effects of PCB exposure depend on a number of factors like procedures and measures used, age at exposure and at testing, and dose and type or combination of PCBs used.
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CEO of Professional Science Editing for Scientists @ prosciediting.com