For example, domains thought to be acting as hubs which belong to diverse superfamilies, with low site coverage, may exploit a single specific surface in their interactions which would allow them to regulate these interactions.
Indeed, in certain situations tumours may exploit these innate inflammatory cells to promote tumour proliferation and invasion (Pollard, 2004).
Thus APP hitches exogenous cargo to cellular anterograde motor machinery for transport, which suggests one mechanism the virus may exploit to travel to the cell surface.
However, paradoxically, TGF- β also modulates processes such as cell invasion, immune regulation and microenvironment modification, which cancer cells may exploit to their advantage.
However, paradoxically, TGF- β1 also modulates cell migration, invasion, angiogenesis, and the microenvironment in ways that cancer cells may exploit to their advantage.
Different cancer cells may exploit different facets of mitochondrial uncoupling.
To decrease the tumour suppressive effect, cancer cells may exploit hypermethylation of the PLA2R1 promoter as gene silencing mechanism [ 12].
Numerous studies have suggested that many epithelial tumor cells may exploit the chemokine systems that normally regulate leukocyte trafficking to metastasize to distant organs.
Therefore, in other cellular membranes, cells may exploit the lipid flipping system by P4-ATPases to regulate the local levels of cytosolic PS.
We speculate that NleL may exploit the free ubiquitin pools in the host cell to exert its function without the canonical substrates.
