Its absence in mouse may explain species-specific differences in fibrate-induced hepatocarcinogenesis.
Its absence in the mouse may explain species-specific differences in fibrate-induced hepatocarcinogenesis.
Our data suggest that the truncated PPARα splice variant functions as an endogenous inhibitor of proliferative and pro-inflammatory genes in human cells and that its absence in mouse may explain species-specific differences in fibrate-induced hepatocarcinogenesis.
Based on our studies, we suggest that the truncated PPARα splice variant provides protective mechanism in acting as an endogenous inhibitor of proliferative and pro-inflammatory genes in human cells and its absence in mouse may explain species-specific differences in fibrate-induced hepatocarcinogenesis.
Divergence in the structure of p57KIP2 suggests functional specialisation in different species and may explain species-specific patterns of expression, subtle differences in the pathologies of human and mouse CDKN1C mutants [ 29], and the absence of imprinting of this gene in the tammar [ 14].
David Tilman, an ecologist at the University of Minnesota in Minneapolis agrees, but cautions that mininiches seen in the meadows may not explain species richness in other habitats.
In contrast, other environmental factors, such as diet, may better explain species differences.
The results suggest that differences in brain size, as a proxy for general cognitive abilities, did not account for variation in performance, but that differential socio-ecological pressures may better explain species differences.
When the genomic locations of one H. pylori ncRNA (nc5490 [ 10]) and one C. jejuni ncRNA (NC4, CJnc170) were compared, this showed that the neighbouring genes are not conserved between the species, which may explain the species-specificity of the ncRNAs.
These diverse reproductive strategies may explain the species success as invader of artificial marine substrates.
