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This suggests that the defects particular to insulin signaling may explain peripheral insulin resistance.
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Increased receptor expression may explain why peripheral nerve damage or inflammation can also change the functional properties of sensory neuron populations such that an increasing percentage of DRG neurons responds to CCL2 application or neurons respond with increased intracellular calcium ion currents and/or frequency of EPSCs [ 82– 84, 99, 101, 135].
Deconditioning fails to explain peripheral skeletal muscle alterations in men with chronic heart failure.
This may explain the process of peripheral sensitization developed during the attack of migraine.
Thus, the fact that basal EGP is unchanged with high-fat feeding combined with relatively unchanged peripheral disposal may explain the fact that fasting, 6 8 pm, and 2 4 am plasma glucose levels remained unchanged (Fig. 2B, Fig. 3A).
88 Thus, possible "off-target" inhibition of these receptors may explain this higher incidence of peripheral and pulmonary edema.
The existence of these factors in most of our patients may explain the difference between the peripheral and CS TIMP-1 levels.
Therefore, the differential susceptibility to tobacco smoke in peripheral receptors/sensors may explain the dissociation of perceptions of the urge-to-cough by citric acid and dyspnea during external resistive loads.
This redistribution keeps peripheral perfusion and may explain the findings from clinical experience that show that severe ductal constriction is well tolerated for some days in the human fetus.
They hypothesised that this increases vasodilatation and potentially decreases maternal peripheral vascular resistance which may explain reduction in preeclamptic seizures [ 28].
This may explain the increased frequency of hip and peripheral fractures observed in an earlier study on Swedish AS patients [ 5].
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