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Assuming that the higher organ cytokine level is a marker of an ongoing inflammation, this may explain organ dysfunction during sepsis.
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This may explain 'the specific organ biology [from lineage-specific gene expression switches] of various mammals' [ 15].
This dysregulation has the potential to cause inappropriate tissue injury that may explain the multiple organ dysfunction observed in severe sepsis.
Several laboratory and observational studies have shown that accelerated apoptosis occurs in sepsis and may explain both the organ failure that is a feature of it and secondary infections that can intervene [ 8- 10].
Some xenobiotics may not only induce DNA damage but also may drive clonal expansion, often at low-dose levels not dissimilar to typical human exposures; such effects may explain the target-organ specificity of some procarcinogens (Lauber et al. 2004; Plíšková et al. 2004).
Commensalism of P. acnes in these organs may explain why they are frequently involved in sarcoidosis.
Involvement of internal organs may explain the suspected increased mortality of NSF patients.
We hypothesized that activation of Gr66a receptors in distinct sensory organs may explain the opposing behavioral responses to lobeline.
If all frequencies contained within the H. cavitympanum calls are transduced by the BP, the relatively simple resonant structure and poor frequency resolution properties of this organ [40] [42] may explain why the frogs showed no obvious behavioral discrimination between AUD and US playback blocks.
This mechanism may explain the development of multiple organ dysfunction syndrome [ 41].
Organ involvement may explain the suspected increased mortality of NSF patients [ 4].
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