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The reduction in juvenile tempo with increasing residency in the UK may explain increasing breast cancer rates in South Asian migrants to the UK [ 41].
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Disordered eating behaviors often seen in people with PTSD symptoms may explain increased cardiometabolic risk.
Increases in tight junction diameter by specific cytokine combinations have been demonstrated and may explain increased DTPA absorption in the setting of inflammation [15].
Several physiopathological mechanisms may explain increased GFAP levels in serum of GBM patients, including disruption of BBB and/or the extent of tumour angiogenesis or tumour necrosis.
Low-grade but significantly increased bacterial dissemination after intestinal barrier dysfunction [13], [37] may explain increased Kyna levels after repeated stress which may not be prevented by 1-MT treatment but is not investigated, yet.
It has been hypothesized that vitamin-D deficiency may explain increased cancer rates [ 33].
This may explain increased stability of mRNA in cells differentiated in the RA condition.
Several mechanisms may explain increased morbidity and mortality, including associated respiratory muscle weakness [ 51], pharyngeal dysfunction, and symptomatic aspiration [ 9].
Finally, we described mechanisms that may explain increased prevalence of invasive NTHi infections over the past 2 decades.
The resulting increased aerobic activity may explain increased substrate (food) demand and thus the striking effects on the overnight starved Plp1tg mice.
Peak PI levels acutely inhibit insulin-mediated glucose disposal, which may explain increased abnormalities with GTT compared with fasting glucose (7, 8).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com