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Since expression in different compartments may explain distinct Notch1 and Notch2 functions, we analyzed the expression pattern of these receptors using immunohistochemical staining as well as transgenic Notch1-GFP [38] and Notch2lacZ knockin [39] reporter mice.
Moreover, environmental conditions that increase or reduce hippocampal neurogenesis may affect the relative contribution of newly generated granule cells to the S- or L-groups that may explain distinct behavioral consequences of altered neurogenesis (Kempermann et al., 1997; Gould and Tanapat, 1999; van Praag et al., 1999).
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The early divergence of low- and high-grade disease may help explain distinct differences in their clinical behavior.
This indicates that distinct mechanisms control endothelial cell attachment at different sites and may explain the distinct requirement of correct N-glycosylation of Treg for homing to the ALN but the not MLN.
Its studio-bound, high-concept slickness seems to jar with current musical trends, which may explain the distinct hint of critical bemusement with which Kaputt's appearance was greeted: even a reviewer who loved it called it "one of the most indefensible albums of all time".
The different microscopic structures between American ginseng and Asian ginseng may explain their distinct distribution patterns of ginsenosides in various tissues.
Our structural studies reveal different binding modes of GL479 to PPARα and PPARγ, which may explain the distinct activation behaviors observed for each receptor.
Likewise, in humans, the cross-reactivity of many anti-HLA-class II monoclonal antibodies with several of the three isotypes may explain why distinct complexes of DP, DQ, and DR with Ii have not been clearly demonstrated to date.
These differences may explain the distinct pharmacological effects of PDE4 inhibition in rodent and human hearts.
The absence of such confounds may explain the distinct heterozygous vocalization findings in the different studies.
Differences in the assembly of macromolecular signaling complexes may explain the distinct biological outcomes.
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