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Chk1 inhibitors may exhibit single agent anti-tumor activity in cancers with underlying DNA repair, DNA damage response or DNA replication defects.
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Evolutionarily related genomes may exhibit single-nucleotide variation (SNV) and short insertion or deletion (indel) variation, but also structural variation (SV) consisting of larger chromosomal deletions, insertions, and rearrangements.
Furthermore, the devices also exhibit single lateral mode emission.
Six other alleles exhibit single substitutions within the 3' untranslated region.
This indicates that this SNP may exhibit an independent fetal single locus association with PTB.
It is well known that solution-grown linear polyethylene single crystals may exhibit different and often complex morphologies and habits.
In nature, M. aeruginosa grows as mucilaginous colonies typically harboring many thousands of cells [41], [42], and recent studies indicate that a single genotype may exhibit various colony morphologies under different environmental conditions [43].
A theoretical model proposes that a single species may exhibit alternative symbiovars depending on the presence of symbiotic plasmids or symbiotic islands [ 2].
Thus, the reasons for the anecdotal reports, if true, that switching from the brand to the generic formulation of phenobarbital may lead to recurrence of seizures are obviously not related to a generally lower bioavailability of the generic formulation, although single dogs may exhibit lower plasma levels after the generic formulation that could be clinically meaningful.
These combinations were all conceived based on the prototypical polypharmacology hypothesis that targeting two different nodes of HCV replication may exhibit superior antiviral activity compared to single drugs and reduced resistance [11].
Clearly, a less simplistic view is that awareness is a large-scale, distributed property [13], in which case no single cortical structure may exhibit a macroscopic activation that co-varies on its own with the conscious percept.
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