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Consequently, T1/ST2 may exert functions in addition to the transduction of IL-33-induced signals.
Recent studies suggest that lncRNAs may exert functions through targeting miRNAs.
We hypothesized that BOK may exert functions that overlap with those of BAK and/or BAX and examined this by generating Bok −/− Bak −/− and Bok −/− Bax −/− mice.
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Given the similarity in the interaction surfaces of σ70 for AsiA and Rsd one could speculate that Rsd may also exert functions other than sequestering the primary sigma factor σ70.
However, TReg may also exert functions independent of inhibition of lymphocyte function, as was shown in a model of LPS-induced acute lung injury (D'Alessio et al, 2009).
It is evident that APP/APLPs are highly complex molecules, that may exert important functions as unprocessed cell surface molecules (APP-FL) as well as functions mediated by their diverse proteolytic fragments.
In conclusion, our findings and those of others still imply that BOK may exert multiple functions, some that overlap with the pro-apoptotic role of BAX/BAK, and others that remain to be determined.
Signals could thus bypass BRAF through ARAF, CRAF, and MOS, which may exert similar functions as BRAF.
Thus, whether miR-181b functions as an oncogene or a tumor suppressor is dependent on the cell and tumor types, and miR-181b may exert different functions under different circumstances.
In addition, Wnt/β-catenin signaling may exert distinct functions in a dose dependent manner.
Interestingly, certain KLKs may exert antiangiogenic functions, since they have been shown to release angiostatin-like peptides by proteolytic processing of plasminogen [81].
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